Skip to main content

The Aesthetic Channel is part of the Informa Markets Division of Informa PLC

  • Informa PLC
  • About us
  • Investor relations
  • Talent

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

 
  • Login
  • Register
  • Login
  • Register
Home
  • Topics
  • Nonsurgical Procedures
  • Surgical Procedures
  • Practice Management
  • Aesthetic Education

SUBSCRIBE NOW

A natural injectable using a regenerative fat-building matrix

  • Jeffrey Frentzen
May 14, 2019
Volume: 
22
Issue: 
3
  • The Aesthetic Guide, Advances in Aesthetic Technology, Aesthetic, Beauty, Editor's Choice, Editorials, Facial Rejuvenation, Feature Articles, Nonsurgical Procedures, Research, Science, Technology, The Aesthetic Guide
fillers, injectables, liposuction, volume, facial rejuvenation, dermatology
Michael Gold, MD Dermatologist Nashville, TN
fillers, injectables, liposuction, volume, facial rejuvenation, dermatology
Rod J. Rohrich, MD, FACS Plastic Surgeon Dallas, TX
fillers, injectables, liposuction, volume, facial rejuvenation, dermatology
Regina M. Fearmonti, MD Plastic and Reconstructive Surgeon San Antonio, TX

Sponsored by MTF Biologics
 
Every so often a new aesthetic innovation turns people’s heads. Such is the case with Renuva® from MTF Biologics, (Edison, N.J.), an off-the-shelf adipose matrix made from donated allograft tissue, which can be injected into soft tissue defects in any body area that fat is naturally occurring. It then acts as a scaffold to allow the body to grow new fat cells.
 
Physicians have used Renuva to address volume loss, liposuction irregularities, scars, hand and facial rejuvenation, and breast contouring.  
 
“Renuva is a unique injectable that uses the matrix surrounding human fat cells, letting us volumize certain defects in the skin,” expressed Michael H. Gold, MD, a dermatologist in Nashville, Tenn. “It works by forming a matrix that becomes adipose tissue over time. I think it will be useful for facial volumization and for any fat-related defect, such as fat atrophy following steroid injections. This is a great concept that most clinicians will find useful.”
 
Renuva allografts retain the structural and endogenous materials found in human fat, such as collagens, growth factors and proteins needed for the matrix to vascularize after injection. This leads to localized adipogenesis as the graft incorporates and remodels.1 
 
According to Rod J. Rohrich, MD, a plastic surgeon in Dallas, Texas, “Renuva  supports the body to rebuild fat, which is very appealing to patients. I use it in the face, head and neck areas, and it works really well. It truly is a natural filler.”
 
RELATED: Off-the-shelf fat injections
 
As reported by Regina M. Fearmonti, MD, a plastic and reconstructive surgeon in San Antonio, Texas, “Having performed fat grafting to address volume loss in the hands and face, I was looking for an in-clinic alternative with comparable results and no donor site. While I have used long-lasting fillers to correct cellulite dimples and liposuction defects, I felt a need for a solution that handles more like fat and with lasting results. Renuva filled both of those needs.”
 
When compared to ordinary hyaluronic acid fillers, “For volumization it has compared nicely,” Dr. Gold reported. “In clinical trials, the patients’ skin quality and tone have shown improvement from baseline.”
 
Regarding volume retention, Dr. Fearmonti noted, “I have been using Renuva for two years. I usually perform larger volume injections over two sessions to avoid overcorrection and to better assess the result once the saline used to reconstitute the product has resorbed. Using that protocol, I have seen maintenance of the final injected volume at two years.”
 
Going forward, Dr. Rohrich is optimistic about Renuva’s potential as a safe, effective advancement in fat grafting. “I’ve used Renuva in patients where it lasted well over a year,” he stated. 
 
“Also, you have a lot more control compared with a regular injectable,” Dr. Rohrich continued. “I think this is the beginning of how we are eventually going to do it. The age of truly replacing like with like in our own bodies has arrived, and this product can actually regrow what has been lost. It is the way to go.”
 
Reference:
1. Kokai et al. (2019). Injectable Allograft Adipose Matrix Supports Adipogenic Tissue Remodeling in the Nude Mouse and Human. Plastic and Reconstructive Surgery.143. 299e-309e. 10.1097/PRS.0000000000005269.
 

Related Articles

  • End your year with a bang!
  • A year in review: Taking a look back at 2019 and a look forward to 2020
  • Women in aesthetics Jean Carruthers, MD: The Botox pioneer
  • Introducing YOU marketing
  • What men want: An update on the male aesthetics market

Resource Topics rightRail

  • Resource Topics
  • Partner Content
  • Advances in Aesthetic Technology
  • Aesthetic Lasers
  • Fat Reduction
  • Vaginal Rejuvenation
  • Wrinkle Treatments
There is currently no available content. Please check back soon.

Current Issue

The Aesthetic Guide November/December 2019
Nov 22, 2019 Vol 22 No 6
Digital Edition
Connect with Us
  • Column 1
    • Home
    • About Us
    • Contact Us
  • Column 2
    • Editorial Info
    • Editorial Board
  • Column 3
    • Advertising Info
  • Column 4
Copyright © 2019. All rights reserved. Informa Markets, a trading division of Informa PLC.
Accessibility | Privacy Policy | Cookie Policy | Terms of Use

We've noticed that you're using an ad blocker

Our content is brought to you free of charge because of the support of our advertisers. To continue enjoying our content, please turn off your ad blocker.

It's off now Dismiss How do I disable my ad blocker?
❌

How to disable your ad blocker for our site:

Adblock / Adblock Plus
  • Click on the AdBlock / AdBlock Plus icon on the top right of your browser.
  • Click “Don’t run on pages on this domain.” OR “Enabled on this site.”
  • Close this help box and click "It's off now".
Firefox Tracking Prevention
  • If you are Private Browsing in Firefox, "Tracking Protection" may casue the adblock notice to show. It can be temporarily disabled by clicking the "shield" icon in the address bar.
  • Close this help box and click "It's off now".
Ghostery
  • Click the Ghostery icon on your browser.
  • In Ghostery versions < 6.0 click “Whitelist site.” in version 6.0 click “Trust site.”
  • Close this help box and click "It's off now".
uBlock / uBlock Origin
  • Click the uBlock / uBlock Origin icon on your browser.
  • Click the “power” button in the menu that appears to whitelist the current website
  • Close this help box and click "It's off now".